Developing and characterizing a two-layered safety switch for cell therapies
Author:
Affiliation:
1. Center for Stem Cell and Translational Immunotherapy (CSTI), Harvard Medical School, Boston, MA, USA
2. Department of Neurosurgery, Brigham and Women’s Hospital, Boston, MA, USA
3. Harvard Stem Cell Institute, Harvard University, Boston, MA, USA
Funder
NIH
Publisher
Informa UK Limited
Subject
Cancer Research,Pharmacology,Oncology,Molecular Medicine
Link
https://www.tandfonline.com/doi/pdf/10.1080/15384047.2023.2232146
Reference17 articles.
1. Adoptive cellular therapies: the current landscape
2. Stem Cells Engineered During Different Stages of Reprogramming Reveal Varying Therapeutic Efficacies
3. Bi-specific molecule against EGFR and death receptors simultaneously targets proliferation and death pathways in tumors
4. Introduction of Exogenous HSV-TK Suicide Gene Increases Safety of Keratinocyte-Derived Induced Pluripotent Stem Cells by Providing Genetic “Emergency Exit” Switch
5. Chimeric Antigen Receptor-Engineered NK-92 Cells: An Off-the-Shelf Cellular Therapeutic for Targeted Elimination of Cancer Cells and Induction of Protective Antitumor Immunity
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1. Correction;Cancer Biology & Therapy;2024-08-19
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