TP53INP2-dependent activation of muscle autophagy ameliorates sarcopenia and promotes healthy aging

Author:

Sebastián David123ORCID,Beltrà Marc234,Irazoki Andrea234,Sala David234,Aparicio Pilar5,Aris Cecilia6,Alibakhshi Esmaeil789,Rubio-Valera Maria1011,Palacín Manuel2412,Castellanos Juan5,Lores Luis7,Zorzano Antonio234

Affiliation:

1. Department of Biochemistry and Physiology, School of Pharmacy and Food Sciences, Universitat de Barcelona, Barcelona, Spain

2. Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain

3. Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Instituto de Salud Carlos III, Madrid, Spain

4. Departament de Bioquímica i Biomedicina Molecular, Facultat de Biologia, Universitat de Barcelona, Barcelona, Spain

5. Department of Orthopedic Surgery and Traumatology, Hospital de Sant Boi Sant Joan de Déu, Sant Boi de Llobregat, Barcelona, Spain

6. Department of Family and Community Medicine, Hospital de Sant Boi Sant Joan de Déu, Sant Boi de Llobregat, Barcelona, Spain

7. Pneumology Department, Hospital de Sant Boi Sant Joan de Déu, Sant Boi de Llobregat, Barcelona, Spain

8. Physical Medicine and Rehabilitation Department, Clinical Research Development Unit, Baqyiatallah Hospital, Faculty of Medicine, Baqyiatallah University of Medical Science, Tehran, Iran

9. Quantitative MR Imaging and Spectroscopy Group, Research Center for Molecular and Cellular Imaging, Advanced Medical Technologies and Equipment Institute, Tehran University of Medical Science, Tehran, Iran

10. Quality and Patient Safety Unit, Hospital de Sant Boi Sant Joan de Déu, Sant Boi de Llobregat, Barcelona, Spain

11. Centro de Investigación Biomédica en Epidemiologia y Salud Pública (CIBERESP), Instituto de Salud Carlos III, Madrid, Spain

12. Centro de Investigación Biomédica de Enfermedades Raras (CIBERER), Instituto de Salud Carlos III, Madrid, Spain

Funder

European Foundation for the Study of Diabetes

Fundació la Marató de TV3

Fundación BBVA

Fundación Ramón Areces

Instituto de Salud Carlos III

Ministerio de Ciencia e Innovación

Publisher

Informa UK Limited

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