Cleavage of SQSTM1/p62 by the Zika virus protease NS2B3 prevents autophagic degradation of viral NS3 and NS5 proteins

Author:

Zhou Peng123,Zhang Qingxiang123,Yang Yueshan123,Wu Wanrong123,Chen Dong123,Zheng Zhenhua4,Jongkaewwattana Anan5,Jin Hui123,Zhou Hongbo123,Luo Rui123ORCID

Affiliation:

1. State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China

2. Key Laboratory of Preventive Veterinary Medicine in Hubei Province, The Cooperative Innovation Center for Sustainable Pig Production, Wuhan, China

3. Key Laboratory of Development of Veterinary Diagnostic Products, Ministry of Agriculture and Rural Affairs of the People’s Republic of China, Wuhan, China

4. Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, China

5. Virology and Cell Technology Research Team, National Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency (NSTDA), Klong Nueng, Thailand

Funder

National Natural Science Foundation of China

Postdoctoral Fellowship Program of CPSF

Fundamental Research Funds for the Central Universities

Natural Science Foundation of Hubei Province

Publisher

Informa UK Limited

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