Spautin-1 promotes PINK1-PRKN-dependent mitophagy and improves associative learning capability in an alzheimer disease animal model

Author:

Yi Juan1ORCID,Wang He-Ling2ORCID,Lu Guang3ORCID,Zhang Hailong1,Wang Lina1,Li Zhen-Yu4,Wang Liming5,Wu Yihua6,Xia Dajing6,Fang Evandro F.27ORCID,Shen Han-Ming8ORCID

Affiliation:

1. School of Basic Medical Sciences, Lanzhou University, Lanzhou, Gansu, China

2. Department of Clinical Molecular Biology, University of Oslo and Akershus University Hospital, Lørenskog, Norway

3. Department of Physiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China

4. College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, China

5. School of Biomedical Sciences, Hunan University, Changsha, China

6. School of Public Health, Zhejiang University, Hangzhou, China

7. The Norwegian Centre on Healthy Ageing (NO-Age), Oslo, Norway

8. Faculty of Health Sciences, Ministry of Education Frontiers Science Center for Precision Oncology, University of Macau, Macau, China

Funder

National Natural Science Foundation of China

Natural Science Foundation of Gansu Province

CAMS Innovation Fund for Medical Sciences

Macau Science and Technology Development Fund

Program for the Ministry of Education “Peptide Drugs” Innovation Team

Universidade de Macau

Publisher

Informa UK Limited

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