Mir221- and Mir222 -enriched adsc-exosomes mitigate PM exposure-exacerbated cardiac ischemia-reperfusion injury through the modulation of the BNIP3-MAP1LC3B-BBC3/PUMA pathway

Author:

Lee Tzu-Lin1,Shen Wen-Chi1,Chen Ya-Chun1,Lai Tsai-Chun123,Lin Shu-Rung45,Lin Shu-Wha6,Yu I-Shing7,Yeh Yen-Hsiu8,Li Tsai-Kun8910,Lee I-Ta11,Lee Chiang-Wen121314,Chen Yuh-Lien1ORCID

Affiliation:

1. Department of Anatomy and Cell Biology, College of Medicine, National Taiwan University, Taipei, Taiwan

2. Department of Life Sciences, College of Life Sciences, National Chung Hsing University, Taichung, Taiwan

3. The iEGG and Animal Biotechnology Center, National Chung Hsing University, Taichung, Taiwan

4. Department of Bioscience Technology, College of Science, Chung Yuan Christian University, Taoyuan, Taiwan

5. Center for Nanotechnology, Chung Yuan Christian University, Taoyuan, Taiwan

6. Department of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University, Taipei, Taiwan

7. Laboratory Animal Center, College of Medicine, National Taiwan University, Taipei, Taiwan

8. Department and Graduate Institute of Microbiology, College of Medicine, National Taiwan University, Taipei, Taiwan

9. Center for Biotechnology, National Taiwan University, Taipei, Taiwan

10. Centers for Genomic and Precision Medicine, National Taiwan University, Taipei, Taiwan

11. School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei, Taiwan

12. Department of Orthopaedic Surgery, Chang Gung Memorial Hospital, Puzi, Chiayi, Taiwan

13. Department of Nursing, Division of Basic Medical Sciences, and Chronic Diseases and Health Promotion Research Center Chang Gung University of Science and Technology, Puzi, Chiayi, Taiwan

14. Research Center for Industry of Human Ecology and Research Center for Chinese Herbal Medicine, Chang Gung University of Science and Technology, Taoyuan, Taiwan

Funder

National Science and Technology Council

Publisher

Informa UK Limited

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