Vitamin D3 activates the autolysosomal degradation function against Helicobacter pylori through the PDIA3 receptor in gastric epithelial cells

Author:

Hu Wei12,Zhang Lin234,Li Ming Xing3,Shen Jing3,Liu Xiao Dong2,Xiao Zhan Gang3,Wu Ding Lan5,Ho Idy H. T.2,Wu Justin C. Y.46,Cheung Cynthia K. Y.46,Zhang Yu Chen2,Lau Alaster H. Y.7,Ashktorab Hassan8910,Smoot Duane T.11,Fang Evandro F.1213,Chan Matthew T. V.2,Gin Tony2,Gong Wei1,Wu William K. K.24,Cho Chi Hin3ORCID

Affiliation:

1. Department of Gastroenterology, Shenzhen Hospital, Southern Medical University, Shenzhen, China;

2. Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong, Hong Kong, China

3. Laboratory of Molecular Pharmacology, Department of Pharmacology, School of Pharmacy, Southwest Medical University, Luzhou, China

4. Institute of Digestive Diseases, State Key Laboratory of Digestive Diseases, LKS Institute of Health Sciences, CUHK Shenzhen Research Institute, The Chinese University of Hong Kong, Hong Kong, China

5. Shenzhen Key Laboratory of Viral Oncology, The Clinical Innovation & Research Center (CIRC), Shenzhen Hospital, Southern Medical University, Shenzhen, China

6. Department of Medicine & Therapeutics, The Chinese University of Hong Kong, Hong Kong, China

7. School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China

8. Department of Medicine, Howard University, Washington, DC, USA

9. Cancer Center, Howard University, Washington, DC, USA

10. Howard University Hospital, Howard University, Washington, DC, USA

11. Department of Internal Medicine, Meharry Medical College, Nashville, TN, USA

12. Laboratory of Molecular Gerontology, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA

13. Department of Clinical Molecular Biology, University of Oslo and Akershus University Hospital, Lørenskog, Norway

Funder

Health and Medical Research Fund

National Natural Science Foundation of China

Science and Technology Planning Project of Luzhou, Sichuan Province, China

Early Career Scheme/General Research Fund from the Hong Kong Research Grant Council

Publisher

Informa UK Limited

Subject

Cell Biology,Molecular Biology

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