Vitamin D3and carbamazepine protect againstClostridioides difficileinfection in mice by restoring macrophage lysosome acidification

Author:

Chan Hung123,Li Qing1234,Wang Xiansong12,Liu Wing Yingzhi12,Hu Wei123,Zeng Judeng123,Xie Chuan123,Kwong Thomas Ngai Yeung345,Ho Idy Hiu Ting123,Liu Xiaodong123,Chen Huarong1234,Yu Jun3456,Ko Ho235,Chan Raphael Chiu Yeung7,Ip Margaret67ORCID,Gin Tony123,Cheng Alfred Sze Lok48,Zhang Lin12345,Chan Matthew Tak Vai123,Wong Sunny Hei34569ORCID,Wu William Ka Kei12346

Affiliation:

1. Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China

2. Peter Hung Pain Research Institute, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China

3. Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China

4. State Key Laboratory of Digestive Diseases, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China

5. Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China

6. Centre for Gut Microbiota Research, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China

7. Department of Microbiology, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China

8. School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China

9. Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore

Funder

National Natural Science Foundation of China

Hong Kong Food and Health Bureau (FHB) Commissioned Health and Medical Research Fund

Publisher

Informa UK Limited

Subject

Cell Biology,Molecular Biology

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