A novel tumor-promoting mechanism of IL6 and the therapeutic efficacy of tocilizumab: Hypoxia-induced IL6 is a potent autophagy initiator in glioblastoma via the p-STAT3-MIR155-3p-CREBRF pathway

Author:

Xue Hao12,Yuan Guang3,Guo Xing12,Liu Qinglin1,Zhang Jinsen12,Gao Xiao1,Guo Xiaofan1,Xu Shugang14,Li Tong1,Shao Qianqian5,Yan Shaofeng2,Li Gang12

Affiliation:

1. Department of Neurosurgery, Qilu Hospital of Shandong University, Jinan, Shandong Province, China

2. Brain Science Research Institute, Shandong University, Jinan, Shandong Province, China

3. Department of Neurosurgery, Central Hospital of Zibo City, Zibo, Shandong Province, China

4. Department of Neurosurgery, Dezhou People's Hospital, Dezhou, Shandong Province,China

5. Institute of Basic Medical Sciences and Key Laboratory of Cardiovascular Proteomics of Shandong Province, Qilu Hospital of Shandong University, Jinan, Shandong Province, China

Publisher

Informa UK Limited

Subject

Cell Biology,Molecular Biology

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