Inhibition of autophagosome-lysosome fusion by ginsenoside Ro via the ESR2-NCF1-ROS pathway sensitizes esophageal cancer cells to 5-fluorouracil-induced cell death via the CHEK1-mediated DNA damage checkpoint

Author:

Zheng Kai12,Li Yan3,Wang Shaoxiang1,Wang Xiao2,Liao Chenghui1,Hu Xiaopeng1,Fan Long1,Kang Qiangrong1,Zeng Yong3,Wu Xuli1,Wu Haiqiang1,Zhang Jian1,Wang Yifei2,He Zhendan1

Affiliation:

1. Department of Pharmacy, School of Medicine, Innovation Platform for Natural Small Molecule Drugs, Shenzhen Key Laboratory of Novel Natural Health Care Products, Engineering Laboratory of Shenzhen Natural Small Molecule Innovative Drugs, Shenzhen University, Shenzhen, China

2. Guangzhou Jinan Biomedicine Research and Development Center, College of Life Science and Technology, Jinan University, Guangzhou, China

3. The First Affiliated Hospital of Kunming Medical University, Kunming, China

Publisher

Informa UK Limited

Subject

Cell Biology,Molecular Biology

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