CCDC88A/GIV promotes HBV replication and progeny secretion via enhancing endosomal trafficking and blocking autophagic degradation

Author:

Wang Xueyu12,Wei Zhiqiang12,Lan Tingyu13,He Yulin1,Cheng Bin1,Li Ruimin1,Chen Hongxia1,Li Fahong24,Liu Guohua1,Jiang Bin15,Lin Yong26,Lu Mengji2,Meng Zhongji137ORCID

Affiliation:

1. Institute of Biomedical Research, Hubei Clinical Research Center for Precise Diagnosis and Treatment of Liver Cancer, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei province, China

2. Institute of Virology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany

3. Department of Infectious Diseases, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei province, China

4. Department of Infectious Diseases,Huashan Hospital, Fudan University, Shanghai, China

5. Department of Hepatobiliary Pancreatic Surgery, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei province, China

6. The Key Laboratory of Molecular Biology of Infectious Diseases Designated by the Chinese Ministry of Education, Institute for Viral Hepatitis, Department of Infectious Diseases, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, China

7. Hubei Key Laboratory of Embryonic Stem Cell Research, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei province, China

Funder

National Major Science and Technology Projects of China

Foundation for Innovative Research Groups of Hubei Provincial Natural Science Foundation

Hubei Province’s Outstanding Medical Academic Leader Program

Project of Hubei University of Medicine

Health Commission of Hubei Province scientific research project

Deutsche Forschungsgemeinschaft

Publisher

Informa UK Limited

Subject

Cell Biology,Molecular Biology

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