Inhibition of the SEC61 translocon by mycolactone induces a protective autophagic response controlled by EIF2S1-dependent translation that does not require ULK1 activity-Reference-Cited by-同舟云学术

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Inhibition of the SEC61 translocon by mycolactone induces a protective autophagic response controlled by EIF2S1-dependent translation that does not require ULK1 activity

Published:2021-08-23 Issue: Volume: Page:1-19
ISSN:1554-8627
Container-title:Autophagy
language:en
Short-container-title:Autophagy

Author:

Hall Belinda S¹^ORCID,Dos Santos Scott J¹^ORCID,Hsieh Louise Tzung-Harn¹^ORCID,Manifava Maria²,Ruf Marie-Thérèse³⁴,Pluschke Gerd³⁴^ORCID,Ktistakis Nicholas²^ORCID,Simmonds Rachel E¹^ORCID

Affiliation:

1. Department of Microbial Sciences, School of Biosciences and Medicine, University of Surrey, Guildford, UK

2. Signaling Programme, Babraham Institute, Cambridge, UK

3. Molecular Immunology, Swiss Tropical and Public Health Institute, Basel, Switzerland

4. Medical Parasitology and Infection Biology Department, University of Basel, Basel, Switzerland

Funder

Wellcome Trust

Publisher

Informa UK Limited

Subject

Cell Biology,Molecular Biology

Link

https://www.tandfonline.com/doi/pdf/10.1080/15548627.2021.1961067

Reference82 articles.

1. Mycolactone: A Polyketide Toxin from Mycobacterium ulcerans Required for Virulence

2. Buruli Ulcer: a Review of the Current Knowledge

3. A Mycobacterium ulcerans Toxin, Mycolactone, Causes Apoptosis in Guinea Pig Ulcers and Tissue Culture Cells

4. Mycolactone impairs T cell homing by suppressing microRNA control of L-selectin expression

5. Mycolactone Inhibits Monocyte Cytokine Production by a Posttranscriptional Mechanism

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1. Inhibition of Caspase-1-dependent pyroptosis alleviates myocardial ischemia/reperfusion injury during cardiopulmonary bypass (CPB) in type 2 diabetic rats;Scientific Reports;2024-08-21

2. Comparative analysis of SEC61A1 mutant R236C in two patient-derived cellular platforms;Scientific Reports;2024-04-25

3. Molecular determinants of SEC61A1 mutant R236C in two patient-derived cellular platforms;2023-12-07

4. Type-I interferons promote innate immune tolerance in macrophages exposed to Mycobacterium ulcerans vesicles;PLOS Pathogens;2023-07-10

5. Mycolactone causes catastrophic Sec61-dependent loss of the endothelial glycocalyx and basement membrane: a new indirect mechanism driving tissue necrosis inMycobacterium ulceransinfection;2023-02-21

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