A family of PIKFYVE inhibitors with therapeutic potential against autophagy-dependent cancer cells disrupt multiple events in lysosome homeostasis-Reference-Cited by-同舟云学术

A family of PIKFYVE inhibitors with therapeutic potential against autophagy-dependent cancer cells disrupt multiple events in lysosome homeostasis

Published:2019-03-08 Issue:10 Volume:15 Page:1694-1718
ISSN:1554-8627
Container-title:Autophagy
language:en
Short-container-title:Autophagy

Author:

Sharma Gaurav¹,Guardia Carlos M.²,Roy Ajit¹,Vassilev Alex¹,Saric Amra²,Griner Lori N.¹,Marugan Juan³,Ferrer Marc³,Bonifacino Juan S.²,DePamphilis Melvin L.¹

Affiliation:

1. Division of Developmental Biology, National Institute of Child Health & Human Development, National Institutes of Health, Bethesda, MD, USA

2. Cell Biology and Neurobiology Branch, National Institute of Child Health & Human Development, National Institutes of Health, Bethesda, MD, USA

3. Division of Pre-Clinical Innovation, NIH Chemical Genomics Center, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, USA

Funder

Eunice Kennedy Shriver National Institute of Child Health and Human Development

Publisher

Informa UK Limited

Subject

Cell Biology,Molecular Biology

Link

https://www.tandfonline.com/doi/pdf/10.1080/15548627.2019.1586257

Reference104 articles.

1. A lysosome-centered view of nutrient homeostasis

2. Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles

3. Autophagy pathway: Cellular and molecular mechanisms