Retinoic acid worsens ATG10-dependent autophagy impairment in TBK1-mutant hiPSC-derived motoneurons through SQSTM1/p62 accumulation-Reference-Cited by-同舟云学术

Retinoic acid worsens ATG10-dependent autophagy impairment in TBK1-mutant hiPSC-derived motoneurons through SQSTM1/p62 accumulation

Published:2019-04-02 Issue:10 Volume:15 Page:1719-1737
ISSN:1554-8627
Container-title:Autophagy
language:en
Short-container-title:Autophagy

Author:

Catanese Alberto¹²^ORCID,Olde Heuvel Florian³,Mulaw Medhanie⁴,Demestre Maria¹,Higelin Julia¹²,Barbi Gotthold⁵,Freischmidt Axel³,Weishaupt Jochen H.³,Ludolph Albert C.³,Roselli Francesco¹³^ORCID,Boeckers Tobias M.¹

Affiliation:

1. Institute of Anatomy and Cell Biology, Ulm University, Ulm, DE, Germany

2. International Graduate School, Ulm University, Ulm, DE, Germany

3. Deptartment of Neurology, Ulm University, Ulm, DE, Germany

4. Institute of Experimental Tumor Research, Ulm University, Ulm, DE, Germany

5. Institute for Human Genetics, Ulm University, Ulm, DE, Germany

Funder

FP7 Ideas: European Research Council

Helmholtz Gesellschaft

DZNE

BMBF

Publisher

Informa UK Limited

Subject

Cell Biology,Molecular Biology

Link

https://www.tandfonline.com/doi/pdf/10.1080/15548627.2019.1589257

Reference75 articles.

1. NF-kappa B activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK-related kinase

2. I B kinase and TANK-binding kinase 1 activate AKT by direct phosphorylation

3. Phosphorylation of the Autophagy Receptor Optineurin Restricts Salmonella Growth

4. TBK1 controls autophagosomal engulfment of polyubiquitinated mitochondria through p62/SQSTM1 phosphorylation

5. Heterozygous TBK1 mutations impair TLR3 immunity and underlie herpes simplex encephalitis of childhood

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