Suppression of autophagy during mitosis via CUL4-RING ubiquitin ligases-mediated WIPI2 polyubiquitination and proteasomal degradation

Author:

Lu Guang1ORCID,Yi Juan1,Gubas Andrea2,Wang Ya-Ting3,Wu Yihua4,Ren Yi1ORCID,Wu Man15,Shi Yin16,Ouyang Chenxi1,Tan Hayden Weng Siong17,Wang Tianru8,Wang Liming1,Yang Nai-Di1,Deng Shuo1,Xia Dajing4,Chen Ruey-Hwa3,Tooze Sharon A.2ORCID,Shen Han-Ming17

Affiliation:

1. Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore

2. Molecular Cell Biology of Autophagy Laboratory, The Francis Crick Institute, London UK

3. Institute of Biological Chemistry, Academia Sinica, Taipei, Taiwan

4. School of Public Health, Zhejiang University, Hangzhou, China

5. School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, China

6. Department of Biochemistry and Molecular Biology, Zhejiang University School of Medicine, Hangzhou, China

7. NUS Graduate School for Integrative Sciences and Engineering, National University of Singapore, Singapore, Singapore

8. Life Sciences Program, Faculty of Arts and Sciences, University of Toronto, Toronto, Canada

Funder

Singapore National Medical Research Council

Publisher

Informa UK Limited

Subject

Cell Biology,Molecular Biology

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