NUPR1 maintains autolysosomal efflux by activating SNAP25 transcription in cancer cells

Author:

Mu Yanchao1,Yan Xiaojie1,Li Ding23,Zhao Dan1,Wang Lingling1,Wang Xiaoyang14,Gao Dan1,Yang Jie1,Zhang Hua1,Li Yanzhe1,Sun Yanan1,Wei Yiliang1,Zhang Zhenfa5,Chang Xinzhong6,Yao Zhi17,Tian Shanshan1,Zhang Kai1,Terada Lance S.8,Ma Zhenyi19ORCID,Liu Zhe1729

Affiliation:

1. 2011 Collaborative Innovation Center of Tianjin for Medical Epigenetics, Tianjin Key Laboratory of Medical Epigenetics, Department of Immunology, Biochemistry and Molecular Biology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China

2. Laboratory of Epigenetics and Tumorigenesis, Tianjin Research Center of Basic Medical Sciences, Tianjin Medical University, Tianjin, 22 Qixiangtai Road, Heping District, Tianjin, China

3. Present address: Department of Clinical Laboratory, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, China

4. Present address: Department of Internal Medicine, The Fifth Hospital of Shijiazhuang, Shijiazhuang, Hebei, China

5. Department of Lung Cancer, Lung Cancer Center, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China

6. Department of Breast Cancer, Breast Cancer Center, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China

7. Key Laboratory of Immune Microenvironment and Disease of the Ministry of Education, Tianjin Medical University, Tianjin, China

8. Department of Internal Medicine, Division of Pulmonary and Critical Care, University of Texas Southwestern Medical Center, Dallas, TX, USA

9. Key Laboratory of Hormones and Development (Ministry of Health), Metabolic Diseases Hospital, Tianjin Institute of Endocrinology, Tianjin Medical University, Tianjin, China

Funder

National Natural Science Foundation of China

Tianjin Municipal Science and Technology Commission

Specialized Research Fund for the Doctoral Program of Higher Education of China

High Technology Research and Development Program of China

HHS | National Institutes of Health

Cancer Prevention and Research Institute of Texas

Publisher

Informa UK Limited

Subject

Cell Biology,Molecular Biology

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