Methyl-β-cyclodextrin restores impaired autophagy flux in Niemann-Pick C1-deficient cells through activation of AMPK-Reference-Cited by-同舟云学术

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Methyl-β-cyclodextrin restores impaired autophagy flux in Niemann-Pick C1-deficient cells through activation of AMPK

Published:2017-06-14 Issue:8 Volume:13 Page:1435-1451
ISSN:1554-8627
Container-title:Autophagy
language:en
Short-container-title:Autophagy

Author:

Dai Sheng¹²,Dulcey Andrés E.¹,Hu Xin¹,Wassif Christopher A.³,Porter Forbes D.³,Austin Christopher P.¹,Ory Daniel S.⁴,Marugan Juan¹,Zheng Wei¹^ORCID

Affiliation:

1. National Center for Advancing Translational Sciences (NCATS), NIH, Bethesda, MD, USA

2. Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China

3. National Institute of Child Health and Human Development, NIH, Bethesda, MD, USA

4. Diabetic Cardiovascular Disease Center, Washington University School of Medicine, St. Louis, MO USA

Publisher

Informa UK Limited

Subject

Cell Biology,Molecular Biology

Link

https://www.tandfonline.com/doi/pdf/10.1080/15548627.2017.1329081

Reference63 articles.

1. Niemann-Pick disease type C

2. Niemann-Pick C1 Disease Gene: Homology to Mediators of Cholesterol Homeostasis

3. Recommendations for the diagnosis and management of Niemann–Pick disease type C: An update

4. Unesterified Cholesterol Accumulation in Late Endosomes/Lysosomes Causes Neurodegeneration and Is Prevented by Driving Cholesterol Export from This Compartment

5. Genetic variations and treatments that affect the lifespan of the NPC1 mouse

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