Deubiquitinase inhibition by WP1130 leads to ULK1 aggregation and blockade of autophagy-Reference-Cited by-同舟云学术

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Deubiquitinase inhibition by WP1130 leads to ULK1 aggregation and blockade of autophagy

Published:2015-09-02 Issue:9 Volume:11 Page:1458-1470
ISSN:1554-8627
Container-title:Autophagy
language:en
Short-container-title:Autophagy

Author:

Drießen Stefan¹,Berleth Niklas¹,Friesen Olena¹,Löffler Antje S¹,Böhler Philip¹,Hieke Nora¹,Stuhldreier Fabian¹,Peter Christoph¹,Schink Kay O²,Schultz Sebastian W²,Stenmark Harald²,Holland Petter³,Simonsen Anne³,Wesselborg Sebastian¹,Stork Björn¹

Affiliation:

1. Institute of Molecular Medicine; Heinrich-Heine-University; Düsseldorf, Germany

2. Department of Biochemistry; Institute for Cancer Research; The Norwegian Radium Hospital; Oslo, Norway

3. Institute of Basic Medical Sciences; Faculty of Medicine; University of Oslo; Oslo, Norway

Publisher

Informa UK Limited

Subject

Cell Biology,Molecular Biology

Link

https://www.tandfonline.com/doi/pdf/10.1080/15548627.2015.1067359

Reference38 articles.

1. The Role of Atg Proteins in Autophagosome Formation

2. Role of AMPK-mTOR-Ulk1/2 in the Regulation of Autophagy: Cross Talk, Shortcuts, and Feedbacks

3. Kinase-Inactivated ULK Proteins Inhibit Autophagy via Their Conserved C-Terminal Domains Using an Atg13-Independent Mechanism

4. ULK1·ATG13·FIP200 Complex Mediates mTOR Signaling and Is Essential for Autophagy

5. Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy

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2. Deubiquitinase USP9X loss sensitizes renal cancer cells to mTOR inhibition;International Journal of Cancer;2023-06

3. Unraveling the Complexity of Regulated Cell Death in Esophageal Cancer: from Underlying Mechanisms to Targeted Therapeutics;International Journal of Biological Sciences;2023

4. Autophagy and beyond: Unraveling the complexity of UNC-51-like kinase 1 (ULK1) from biological functions to therapeutic implications;Acta Pharmaceutica Sinica B;2022-10

5. Intracellular Toxic Advanced Glycation End-Products in 1.4E7 Cell Line Induce Death with Reduction of Microtubule-Associated Protein 1 Light Chain 3 and p62;Nutrients;2022-01-13

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