Induction of autophagy increases the proteolytic activity of reservosomes during Trypanosoma cruzi metacyclogenesis

Author:

Losinno Antonella Denise12,Martínez Santiago José1ORCID,Labriola Carlos Alberto3,Carrillo Carolina4,Romano Patricia Silvia12ORCID

Affiliation:

1. Laboratorio de Biología de Trypanosoma Cruzi y la célula hospedadora, Instituto de Histología y Embriología (IHEM-CONICET), Mendoza, Argentina

2. Facultad de Ciencias Médicas, Universidad Nacional de Cuyo (FCM-UNCUYO), Mendoza, Argentina

3. Laboratorio de Biología estructural y celular, Fundación Instituto Leloir (FIL-CONICET), Buenos Aires, Argentina

4. Laboratorio de Parasitología molecular y bioquímica, Instituto de Ciencias y Tecnología Dr. César Milstein (ICT—CONICET), Buenos Aires, Argentina

Funder

Fondo para la Investigación Científica y Tecnológica

Publisher

Informa UK Limited

Subject

Cell Biology,Molecular Biology

Reference49 articles.

1. Chagas disease (American tripanosomiasis) [Internet]. World Health Organization: Geneva (CH); 2019 [cited 2019 Jun 20]. Available from: https://www.who.int/news-room/fact-sheets/detail/chagas-disease-(american-trypanosomiasis)

2. Experimental and Clinical Treatment of Chagas Disease: A Review

3. Cruzipain: An Update on its Potential as Chemotherapy Target against the Human Pathogen Trypanosoma cruzi

4. The Major Cysteine Proteinase of Trypanosoma cruzi: A Valid Target for Chemotherapy of Chagas Disease

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