Impact of differential and time-dependent autophagy activation on therapeutic efficacy in a model of Huntington disease-Reference-Cited by-同舟云学术

Impact of differential and time-dependent autophagy activation on therapeutic efficacy in a model of Huntington disease

Published:2020-05-06 Issue:6 Volume:17 Page:1316-1329
ISSN:1554-8627
Container-title:Autophagy
language:en
Short-container-title:Autophagy

Author:

Brattås Per Ludvik¹^ORCID,Hersbach Bob A.¹,Madsen Sofia¹,Petri Rebecca¹,Jakobsson Johan¹^ORCID,Pircs Karolina¹^ORCID

Affiliation:

1. Laboratory of Molecular Neurogenetics, Department of Experimental Medical Science, Wallenberg Neuroscience Center and Lund Stem Cell Center, Lund University, Lund, Sweden

Funder

Crafoordska Stiftelsen

Greta och Johan Kocks stiftelser Research

Hjärnfonden

Kungliga Fysiografiska Sällskapet i Lund

Anna-Lisa Rosenberg Fund for Neurological Research

Thelma Zoéga Fund for Medical Research

Swedish Government Initiative for Strategic Research Areas

Swedish excellence project Basal Ganglia Disorders Linnaeus Consortium

Stiftelsen Lars Hiertas Minne

Stiftelsen Olle Engkvist Byggmästare

Stiftelsen för Strategisk Forskning

Thorsten och Elsa Segerfalks Stiftelse

Tore Nilsons Stiftelse för Medicinsk Forskning

Vetenskapsrådet

Åhlén-stiftelsen

Åke Wiberg Stiftelse

Publisher

Informa UK Limited

Subject

Cell Biology,Molecular Biology

Link

https://www.tandfonline.com/doi/pdf/10.1080/15548627.2020.1760014

Reference54 articles.

1. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes

2. Expression of Normal and Mutant Huntingtin in the Developing Brain

3. Predictors of phenotypic progression and disease onset in premanifest and early-stage Huntington's disease in the TRACK-HD study: analysis of 36-month observational data

4. CAG Repeat Not Polyglutamine Length Determines Timing of Huntington’s Disease Onset

5. Huntingtin Aggregation Impairs Autophagy, Leading to Argonaute-2 Accumulation and Global MicroRNA Dysregulation

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