HFE inhibits type I IFNs signaling by targeting the SQSTM1-mediated MAVS autophagic degradation

Author:

Liu Juan12,Wu Xiaopeng12,Wang Hailong12,Wei Jiayu23,Wu Qian2ORCID,Wang Xingbo12,Yan Yan12,Cui Jun4ORCID,Min Junxia3ORCID,Wang Fudi23,Zhou Jiyong12

Affiliation:

1. MOA Key Laboratory of Animal Virology, Center for Veterinary Sciences, Zhejiang University, Hangzhou, PR China

2. State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, PR China

3. School of Public Health, Institute of Translational Medicine, Zhejiang University School of Medicine, Hangzhou, PR China

4. MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, Guangdong, PR China

Funder

China Agriculture Research System

National R&D program project of China

Natural Science Foundation of China

Publisher

Informa UK Limited

Subject

Cell Biology,Molecular Biology

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