Equine lentivirus counteracts SAMHD1 restriction by Rev-mediated degradation of SAMHD1 via the BECN1-dependent lysosomal pathway
Author:
Affiliation:
1. State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, the Chinese Academy of Agricultural Sciences, Harbin, China
Funder
National Natural Science Foundation of China
Natural Science Foundation of Heilongjiang Province
Publisher
Informa UK Limited
Subject
Cell Biology,Molecular Biology
Link
https://www.tandfonline.com/doi/pdf/10.1080/15548627.2020.1846301
Reference64 articles.
1. SAMHD1: At the Crossroads of Cell Proliferation, Immune Responses, and Virus Restriction
2. SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx
3. Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein
4. HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase
5. SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates
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