Rapamycin prevents spontaneous abortion by triggering decidual stromal cell autophagy-mediated NK cell residence

Author:

Lu Han12,Yang Hui-Li23,Zhou Wen-Jie4,Lai Zhen-Zhen2,Qiu Xue-Min23,Fu Qiang5,Zhao Jian-Yuan67,Wang Jian1,Li Da-Jin12,Li Ming-Qing123ORCID

Affiliation:

1. NHC Key Lab of Reproduction Regulation (Shanghai Institute of Planned Parenthood Research), Hospital of Obstetrics and Gynecology, Shanghai Medical School, Fudan University, Shanghai, People’s Republic of China

2. Laboratory for Reproductive Immunology, Institute of Obstetrics and Gynecology, Hospital of Obstetrics and Gynecology, Shanghai Medical School, Fudan University, Shanghai, People’s Republic of China

3. Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Hospital of Obstetrics and Gynecology, Shanghai Medical School, Fudan University, Shanghai, People’s Republic of China

4. Center of Reproductive Medicine of Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China

5. Department of Immunology, Binzhou Medical College, Yantai, People’s Republic of China

6. State Key Laboratory of Genetic Engineering, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai, People’s Republic of China

7. Institute of Metabolism and Integrative Biology (IMIB), School of Life Sciences, Fudan University, Shanghai, People’s Republic of China

Funder

National Natural Science Foundation of China

National Key Research and Development Program of China

Innovation-oriented Science and Technology Grant from NPFPC Key Laboratory of Reproduction Regulation

Program for Zhuoxue of Fudan University

Publisher

Informa UK Limited

Subject

Cell Biology,Molecular Biology

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