Sensitive ELISA-based detection method for the mitophagy marker p-S65-Ub in human cells, autopsy brain, and blood samples

Author:

Watzlawik Jens O.1,Hou Xu1,Fricova Dominika1,Ramnarine Chloe1,Barodia Sandeep K.2ORCID,Gendron Tania F.13,Heckman Michael G.4,DeTure Michael1,Siuda Joanna5,Wszolek Zbigniew K.6,Scherzer Clemens R.7,Ross Owen A.13,Bu Guojun13ORCID,Dickson Dennis W.13,Goldberg Matthew S.28ORCID,Fiesel Fabienne C.13ORCID,Springer Wolfdieter13ORCID

Affiliation:

1. Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA

2. Center for Neurodegeneration and Experimental Therapeutics, The University of Alabama at Birmingham, Birmingham, AL, USA

3. Neuroscience PhD Program, Mayo Clinic Graduate School of Biomedical Sciences, Jacksonville, FL, USA

4. Division of Biomedical Statistics and Informatics, Mayo Clinic, Jacksonville, FL, USA

5. Department of Neurology, Medical University of Silesia, Katowice, Poland

6. Department of Neurology, Mayo Clinic, Jacksonville, FL, USA

7. Center for Advanced Parkinson Research, Harvard Medical School, Brigham and Women’s Hospital, Boston, MA, USA

8. Department of Neurology, Department of Neurobiology, The University of Alabama at Birmingham, Birmingham, AL, USA

Funder

Michael J. Fox Foundation for Parkinson’s Research

National Institutes of Health

National Institute of Neurological Disorders and Stroke

National Institute of Aging

Department of Defense Congressionally Directed Medical Research Programs

Department of Health - Ed and Ethel Moore Alzheimer’s Disease Research Program

Mayo Clinic Foundation and the Center for Biomedical Discovery

Mayo Clinic Alzheimer Disease Research Center

American Parkinson Disease Association

Younkin Scholar Program

Mayo Clinic Center for Individualized Medicine

The Sol Goldman Charitable Trust

Donald G. and Jodi P. Heeringa Family

Haworth Family Professorship in Neurodegenerative Diseases fund

The Albertson Parkinson’s Research Foundation

Harvard NeuroDiscovery Center

Massachusetts Alzheimer’s Disease Research Center

Publisher

Informa UK Limited

Subject

Cell Biology,Molecular Biology

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