SARS-CoV-2 nonstructural protein 6 triggers endoplasmic reticulum stress-induced autophagy to degrade STING1

Author:

Jiao Pengtao1,Fan Wenhui1,Ma Xiaoya23,Lin Runshan13,Zhao Yuna14,Li Yabo14,Zhang He5,Jia Xiaojuan6,Bi Yuhai136,Feng Xiaoli7,Li Minghua7,Liu Wenjun1345,Zhang Ke2,Sun Lei13

Affiliation:

1. CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China

2. Key Laboratory of Molecular Virology and Immunology, Institute Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai, China

3. University of Chinese Academy of Sciences, Beijing, China

4. State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources & Laboratory of Animal Infectious Diseases, College of Animal Sciences and Veterinary Medicine, Guangxi University, Nanning, Guangxi, China

5. Institute of Infectious Diseases, Shenzhen Bay Laboratory, Shenzhen, Guangdong, China

6. The Biological Safety Level-3 (BSL-3) Laboratory of Institute of Microbiology, Chinese Academy of Sciences, Beijing, China

7. Kunming National High-Level Biosafety Research Center for Non-Human Primates, Center for Biosafety Mega-Science, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China

Funder

National Key Research and Development Program of China

Strategic Priority Research Program of Chinese Academy of Sciences

National Natural Science Foundation of China

Chinese Academy of Sciences

Publisher

Informa UK Limited

Subject

Cell Biology,Molecular Biology

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