Strategies for antimicrobial peptide coatings on medical devices: a review and regulatory science perspective

Author:

Kazemzadeh-Narbat Mehdi1ORCID,Cheng Hao234,Chabok Rosa235,Alvarez Mario Moisés2367,de la Fuente-Nunez Cesar8ORCID,Phillips K. Scott9ORCID,Khademhosseini Ali1011121314

Affiliation:

1. Office of Device Evaluation, Center for Devices and Radiological Health, US Food and Drug Administration, Silver Spring, MD, USA

2. Biomaterials Innovation Research Center, Division of Biomedical Engineering, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA

3. Harvard-Massachusetts Institute of Technology, Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA, USA

4. Department of Orthopaedic Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, China

5. DeBusk College of Osteopathic Medicine, Lincoln Memorial University, Harrogate, TN, USA

6. Microsystems Technologies Laboratories, MIT, Cambridge, MA, USA

7. Centro de Biotecnología-FEMSA, Tecnológico de Monterrey, Monterrey, México

8. Machine Biology Group, Departments of Psychiatry and Microbiology, Institute for Biomedical Informatics, Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, Penn Institute for Computational Science, and Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA

9. Division of Biology, Chemistry and Materials Science, Office of Science and Engineering Laboratories, Center for Devices and Radiological Health, US Food and Drug Administration, Silver Spring, MD, USA

10. Department of Bioengineering, Henry Samueli School of Engineering and Applied Sciences, University of California-Los Angeles, Los Angeles, CA, USA

11. Department of Radiology, David Geffen School of Medicine, University of California-Los Angeles, Los Angeles, CA, USA

12. Department of Chemical and Biomolecular Engineering, Henry Samueli School of Engineering and Applied Sciences, University of California-Los Angeles, Los Angeles, CA, USA

13. Center for Minimally Invasive Therapeutics (C-MIT), University of California-Los Angeles, Los Angeles, CA, USA

14. Department of Bioindustrial Technologies, College of Animal Bioscience and Technology, Konkuk University, Seoul, Republic of Korea

Funder

Institute for Diabetes, Obesity, and Metabolism

Penn Mental Health AIDS Research Center of the University of Pennsylvania

Publisher

Informa UK Limited

Subject

Applied Microbiology and Biotechnology,General Medicine,Biotechnology

Reference180 articles.

1. Medical devices on chips

2. U.S.F.D. Administration, overview of regulatory requirements: medical devices – transcript; 2018. [Accessed 2018 Oct 26]. https://www.fda.gov/Training/CDRHLearn/ucm281656.htm.

3. Biofilms, medical devices, and antibiofilm technology: Key messages from a recent public workshop

4. Analytical Challenges of Microbial Biofilms on Medical Devices

5. Covalent immobilization of antimicrobial peptides (AMPs) onto biomaterial surfaces

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