The nonalcoholic steatohepatitis (NASH) drug development graveyard: established hurdles and planning for future success

Author:

Drenth Joost P.H.1,Schattenberg Jörn M.23ORCID

Affiliation:

1. Department of Gastroenterology and Hepatology, Radboud University Medical Centre, Nijmegen, The Netherlands

2. Department of Medicine, University Medical Centre of the Johannes Gutenberg-University, Mainz, Germany

3. Metabolic Liver Research Program, University Medical Centre of the Johannes Gutenberg-University, Mainz, Germany

Publisher

Informa UK Limited

Subject

Pharmacology (medical),Pharmacology,General Medicine

Reference60 articles.

1. Nonalcoholic Fatty Liver Disease 2020: The State of the Disease

2. Shetty A, Syn WK. Health and economic burden of nonalcoholic fatty liver disease in the United States and its impact on veterans. Federal practitioner: for the health care professionals of the VA, DoD, and PHS. 2019;36(1):14–19.

3. [cited 2020 Oct 23]. Available from: https://www.reportsanddata.com/report-detail/non-alcoholic-steatohepatitis-nash-market

4. JKB-121 in patients with nonalcoholic steatohepatitis: A phase 2 double blind randomized placebo control study

5. Metabolic Inflammation—A Role for Hepatic Inflammatory Pathways as Drivers of Comorbidities in Nonalcoholic Fatty Liver Disease?

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