ALZT-OP1: an experimental combination regimen for the treatment of Alzheimer’s disease

Author:

Lozupone Madia1ORCID,Berardino Giuseppe2,Mollica Anita2,Sardone Rodolfo3,Dibello Vittorio4,Zupo Roberta3ORCID,Lampignano Luisa3,Castellana Fabio3,Bortone Ilaria3ORCID,Stallone Roberta5,Daniele Antonio67,Altamura Mario2,Bellomo Antonello2,Solfrizzi Vincenzo8,Panza Francesco3ORCID

Affiliation:

1. Neurodegenerative Disease Unit, Department of Basic Medicine, Neuroscience, and Sense Organs, University of Bari Aldo Moro, Bari, Italy

2. Psychiatric Unit, Department of Clinical & Experimental Medicine, University of Foggia, Foggia, Italy

3. Unit of Research Methodology and Data Sciences for Population Health, National Institute of Gastroenterology and Research Hospital IRCCS “S. De Bellis” Castellana Grotte, Bari, Italy

4. Department of Orofacial Pain and Dysfunction, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, The Netherlands

5. Neuroscience and Education, Human Resources Excellence in Research, University of Foggia, Foggia, Italy

6. Department of Neuroscience, Catholic University of Sacred Heart, Rome, Italy

7. Neurology Unit, IRCCS Fondazione Policlinico Universitario A. Gemelli, Rome, Italy

8. “Cesare Frugoni” Internal and Geriatric Medicine and Memory Unit, University of Bari “Aldo Moro”, Bari, Italy

Funder

This paper was not funded

Publisher

Informa UK Limited

Subject

Pharmacology (medical),Pharmacology,General Medicine

Reference105 articles.

1. Alzheimer’s Disease Facts and Figures. 2021. Last accessed: March 7, 2022. Available from: https://www.alz.org/alzheimers-dementia/facts-figures

2. Cavazzoni P. FDA’s decision to approve new treatment for Alzheimer’s disease. FDA, 2021. Cited March 7, 2022. https://www.fda.gov/drugs/news-events-human-drugs/fdas-decisionapprove-new-treatment-alzheimers-disease

3. National Institute on Aging–Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease

4. Neuroinflammation in Alzheimer's disease

5. Exploring the Etiological Links behind Neurodegenerative Diseases: Inflammatory Cytokines and Bioactive Kynurenines

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