Tofacitinib for the treatment of ulcerative colitis
Author:
Publisher
Informa UK Limited
Subject
Pharmacology (medical),Pharmacology,General Medicine
Link
http://www.tandfonline.com/doi/pdf/10.1080/13543784.2016.1189900
Reference71 articles.
1. Ulcerative colitis
2. Combinatorial Effects of Diet and Genetics on Inflammatory Bowel Disease Pathogenesis
3. Human Gut Dendritic Cells Drive Aberrant Gut-specific T-cell Responses in Ulcerative Colitis, Characterized by Increased IL-4 Production and Loss of IL-22 and IFNγ
4. IL-9 and its receptor are predominantly involved in the pathogenesis of UC
5. TH9 cells that express the transcription factor PU.1 drive T cell–mediated colitis via IL-9 receptor signaling in intestinal epithelial cells
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2. Targeting Lineage-Specific Transcription Factors and Cytokines of the Th17/Treg Axis by Novel 1,3,4-Oxadiazole Derivatives of Pyrrolo[3,4-d]pyridazinone Attenuates TNBS-Induced Experimental Colitis;International Journal of Molecular Sciences;2022-08-31
3. Topical Administration of 0.3% Tofacitinib Suppresses M1 Macrophage Polarization and Allograft Corneal Rejection by Blocking STAT1 Activation in the Rat Cornea;Translational Vision Science & Technology;2022-03-30
4. Discovery of a Colon-Targeted Azo Prodrug of Tofacitinib through the Establishment of Colon-Specific Delivery Systems Constructed by 5-ASA–PABA–MAC and 5-ASA–PABA–Diamine for the Treatment of Ulcerative Colitis;Journal of Medicinal Chemistry;2022-03-11
5. Tofacitinib inhibits inflammatory cytokines from ulcerative colitis and healthy mucosal explants and is associated with pSTAT1/3 reduction in T-cells;American Journal of Physiology-Gastrointestinal and Liver Physiology;2021-03-01
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