A clinical approach to treatment resistance in depressed patients: What to do when the usual treatments don’t work well enough?

Author:

Dodd Seetal1234ORCID,Bauer Michael5ORCID,Carvalho Andre F.16ORCID,Eyre Harris17,Fava Maurizio8,Kasper Siegfried9ORCID,Kennedy Sidney H.10ORCID,Khoo Jon-Paul11,Lopez Jaramillo Carlos12,Malhi Gin S.131415,McIntyre Roger S.61617,Mitchell Philip B.18ORCID,Castro Angela Marianne Paredes1ORCID,Ratheesh Aswin419,Severus Emanuel5ORCID,Suppes Trisha20,Trivedi Madhukar H.21,Thase Michael E.22,Yatham Lakshmi N.23,Young Allan H.24ORCID,Berk Michael123419ORCID

Affiliation:

1. IMPACT – the Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Deakin University, Geelong, Australia

2. Department of Psychiatry, University of Melbourne, Melbourne, Australia

3. Barwon Health, University Hospital Geelong, Geelong, Australia

4. Centre for Youth Mental Health, University of Melbourne, Melbourne, Australia

5. Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Technische Universität Dresden, Germany

6. Department of Psychiatry, University of Toronto and Centre for Addiction and Mental Health (CAMH), Toronto, Canada

7. Discipline of Psychiatry, School of Medicine, The University of Adelaide, Adelaide, Australia

8. Depression Clinical and Research Program, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA

9. Center for Brain Research, Medical University of Vienna, Vienna, Austria

10. Department of Psychiatry, University of Toronto and Centre for Depression and Suicide Studies, St Michael’s Hospital, Toronto, Canada

11. Toowong Specialist Clinic, Toowong, Australia

12. Department of Psychiatry, Universidad de Antioquia, Medellín, Colombia

13. Department of Psychiatry, Faculty of Medicine and Health, Northern Clinical School, The University of Sydney, Sydney, Australia

14. Academic Department of Psychiatry, Royal North Shore Hospital, Northern Sydney Local Health District, St Leonards, Australia

15. CADE Clinic, Royal North Shore Hospital, Northern Sydney Local Health District, St Leonards, Australia

16. Mood Disorders Psychopharmacology Unit, Toronto, Canada

17. Brain and Cognition Discovery Foundation, Toronto, Canada

18. School of Psychiatry, University of New South Wales, and Black Dog Institute, Sydney, Australia

19. Orygen The National Centre of Excellence in Youth Mental Health, Parkville, Australia

20. VA Health Care System, Palo Alto, CA, and Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA, USA

21. Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX, USA

22. Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA

23. Department of Psychiatry, University of British Columbia, Vancouver, Canada

24. Department of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, King’s College London & South London and Maudsley NHS Foundation Trust, Bethlem Royal Hospital, Monks Orchard Road, Beckenham, Kent, UK

Funder

National Health and Medical Research Council

Publisher

Informa UK Limited

Subject

Biological Psychiatry,Psychiatry and Mental health

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