Extended-release morphine sulfate and naltrexone hydrochloride (EMBEDA): naltrexone-associated withdrawal and abuse-related effects in patients with chronic pain and recreational opioid users

Author:

Setnik Beatrice1,Sommerville Kenneth W.12,Pixton Glenn C.1,Webster Lynn3

Affiliation:

1. Pfizer Inc, Durham, NC, USA;

2. Department of Neurology, Duke University Medical Center, Durham, NC, USA;

3. PRA Health Sciences, Salt Lake City, UT, USA

Funder

Pfizer

Pfizer Inc

Publisher

Informa UK Limited

Subject

General Medicine

Reference26 articles.

1. null

2. Increases in Drug and Opioid Overdose Deaths — United States, 2000–2014

3. Substance Abuse and Mental Health Services Administration. Drug abuse warning network, 2011: National estimates of drug-related emergency department visits. HHS Publication No. (SMA) 13-4760, DAWN Series D-39. Rockville, MD: SAMHSA; 2013. Available at: http://www.samhsa.gov/data/2k13/DAWN2k11ED/DAWN2k11ED.htm [Last accessed March 8, 2017]

4. Current and future development of extended-release, abuse-deterrent opioid formulations in the United States

5. Current approaches in tamper-resistant and abuse-deterrent formulations

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