A new formulation of levothyroxine engineered to meet new specification standards

Author:

Lipp Hans-Peter1,Hostalek Ulrike2

Affiliation:

1. University Hospital Tübingen, Germany;

2. Global Medical Affairs, Merck KGaA, Darmstadt, Germany

Publisher

Informa UK Limited

Subject

General Medicine

Reference26 articles.

1. National Institute for Health and Clinical Excellence. Clinical knowledge summaries. Hypothyroidism. NICE, UK; last revised June 2018. Available at: https://cks.nice.org.uk/hypothyroidism [Last accessed September 2018]

2. Guidelines for the Treatment of Hypothyroidism: Prepared by the American Thyroid Association Task Force on Thyroid Hormone Replacement

3. Frellick M. Top-selling, top-prescribed drugs for 2016. Medscape; October 2, 2017. Available at https://www.medscape.com/viewarticle/886404 [Last accessed September 2018]

4. Medicines and Healthcare products Regulatory Agency. Levothyroxine tablet products: a review of clinical & quality considerations. MHRA, UK; 2013. Available at: www.gov.uk/government/publications/levothyroxine-a-review-of-clinical-and-quality-considerations [Last accessed February 22, 2016]

5. US Department of Health and Human Services Food and Drug Administration Center for Drug Evaluation and Research (CDER). Guidance for industry: levothyroxine sodium tablets – in vivo pharmacokinetic and bioavailability studies and in vitro dissolution testing; CDER; 2000. Available at: www.fda.gov/cder/guidance/index.htm [Last accessed February 22, 2016]

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