1. Center for Clinical Pharmacology, The Third Xiangya Hospital, Central South University, Changsha, China
2. Department of Pharmacy, The Third Xiangya Hospital, Central South University, Changsha, China
3. State Key Laboratory of High Performance Computing, College of Computer, National University of Defense Technology, Changsha, China
4. School of Mathematics and Statistics, Central South University, Changsha, China
5. Research Center of Drug Clinical Evaluation of Central South University, Changsha, China