Efficacy and effectiveness of valsartan/amlodipine and valsartan/amlodipine/hydrochlorothiazide in hypertension: randomized controlled versus observational studies

Author:

Sison Jorge1,Vega Rosa María Ríos2,Dayi Hu3,Bader Giovanni4,Brunel Patrick4

Affiliation:

1. Medical Center Manila, Manila, Philippines;

2. Hospital General Zapopan, Jalisco, Mexico;

3. Department of Cardiology, Peking University People’s Hospital, Beijing, China;

4. Novartis Pharma AG, Basel, Switzerland

Publisher

Informa UK Limited

Subject

General Medicine

Reference51 articles.

1. Importance of Observational Studies in Clinical Practice

2. How well do randomized controlled trial data generalize to ‘real-world’ clinical practice settings? A comparison of two generalized anxiety disorder studies

3. Use of real-world evidence to support regulatory decision-making for medical devices: Guidance for industry and Food and Drug Administration staff. Available at: https://www.fda.gov/downloads/medicaldevices/deviceregulationandguidance/guidancedocuments/ucm513027.pdf [Last accessed 13 June 2017]

4. Blood pressure lowering for prevention of cardiovascular disease and death: a systematic review and meta-analysis

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