Systematic literature review and network meta-analysis of cladribine tablets versus alternative disease-modifying treatments for relapsing–remitting multiple sclerosis

Author:

Siddiqui Mohd Kashif1,Khurana Inderpreet Singh1,Budhia Sangeeta2,Hettle Robert2,Harty Gerard3,Wong Schiffon L.4

Affiliation:

1. Parexel International (Heron commercialization), Chandigarh, UT, India;

2. Parexel International, London, UK;

3. Merck Serono Ltd, Feltham, Middlesex, UK;

4. EMD Serono Inc., Billerica, MA, USA

Publisher

Informa UK Limited

Subject

General Medicine

Reference63 articles.

1. Multiple Sclerosis: Pathogenesis and Treatment

2. Guideline on Clinical Investigation of Medicinal Products for the Treatment of Multiple Sclerosis. Doc. Ref. EMA/CHMP/771815/2011, Rev. 2. London, UK: European Medicines Agency (EMA) Committee for Medicinal Products for Human Use (CHMP), 26 March 2015. Available at: http://www.ema.europa.eu/docs/en_GB/document_library/Scientific_guideline/2015/03/WC500185161.pdf [Last accessed 14 June 2017]

3. Multiple sclerosis

4. Benefit–Risk of Therapies for Relapsing–Remitting Multiple Sclerosis: Testing the Number Needed to Treat to Benefit (NNTB), Number Needed to Treat to Harm (NNTH) and the Likelihood to be Helped or Harmed (LHH): A Systematic Review and Meta-Analysis

5. A Network Meta-Analysis of Efficacy and Evaluation of Safety of Subcutaneous Pegylated Interferon Beta-1a versus Other Injectable Therapies for the Treatment of Relapsing-Remitting Multiple Sclerosis

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