Clinical development and evaluation of a VEGF-D assay in plasma from patients with metastatic colorectal cancer in the RAISE study

Author:

Taniguchi Hiroya12,Yoshino Takayuki1,Yamaguchi Kensei3,Yamazaki Kentaro4,Nixon Andrew B.5,Tabernero Josep6,Van Cutsem Eric7,Robling Kim R.8,Abada Paolo B.9,Hozak Rebecca R.10,Siegel Robert11ORCID,Fill Jeffrey A.8,Wijayawardana Sameera12,Walgren Richard A.9,Giles Brendan13,Jones Abby13,Pitts Kelly R.13,Drove Nora9,Muro Kei2

Affiliation:

1. Department of Gastroenterology and Gastrointestinal Oncology, National Cancer Center Hospital East, Kashiwa, Japan

2. Department of Clinical Oncology, Aichi Cancer Center Hospital, Nagoya, Japan

3. Department of Gastroenterological Chemotherapy, Cancer Institute Hospital of Japanese Foundation for Cancer Research, Tokyo, Japan

4. Division of Gastrointestinal Oncology, Shizuoka Cancer Center, Shunt-gun, Japan

5. Department of Medicine, Duke University School of Medicine, Durham, NC, USA

6. Medical Oncology Department, Vall d’Hebron University Hospital and Institute of Oncology (VHIO), IOB-Quiron, UVic-UCC, Barcelona, Spain

7. Digestive Oncology, University Hospitals Leuven and Kuleuven, Leuven, Belgium

8. Clinical Diagnostics Laboratory, Eli Lilly and Company, Indianapolis, IN, USA

9. Oncology Division, Eli Lilly and Company, Indianapolis, IN, USA

10. Oncology Business Unit – Patient Tailoring & Global Strategic Planning, Eli Lilly and Company, Indianapolis, IN, USA

11. Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN, USA

12. Statistics – Oncology, Eli Lilly and Company, Indianapolis, IN, USA

13. Corgenix Inc., Broomfield, CO, USA

Publisher

Informa UK Limited

Subject

General Medicine

Reference24 articles.

1. World Health Organization [Internet]. Cancer. Fact Sheets, Vol. 12. Geneva (Switzerland): World Health Organization; 2018 [cited 2020 June 06]. Available from: https://www.who.int/news-room/fact-sheets/detail/cancer

2. Antagonist antibodies to vascular endothelial growth factor receptor 2 (VEGFR-2) as anti-angiogenic agents

3. Ramucirumab monotherapy for previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma (REGARD): an international, randomised, multicentre, placebo-controlled, phase 3 trial

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