1. Department of Obstetrics and Gynaecology, University of Pretoria, Arcadia, South Africa;
2. Biomedical Research and Innovation Platform, South African Medical Research Council, Tygerberg, South Africa;
3. Division of Medical Physiology, Faculty of Medicine and Health Sciences, University of Stellenbosch, Stellenbosch, South Africa;
4. Department of Internal Medicine, University of Pretoria, Arcadia, South Africa