Basis of Selectivity of Antibacterial Diaminopyrimidines
Author:
Affiliation:
1. Division of Molecular Genetics and Microbiology
2. Division of Organic Chemistry, Burroughs Wellcome Co, Research Triangle Park, NC 27709 (USA).
Publisher
Informa UK Limited
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology,Oncology
Link
https://www.tandfonline.com/doi/pdf/10.1080/1120009X.1993.11741086
Reference28 articles.
1. Hitchings GH. Nobel lecture in physiology or medicine-1988: selective inhibitors of dihydrofolate reductase. In Vitro Cell Develop Biol 1989; 25: 303–10.
2. Blakley RL. Dihydrofolate reductase. In: Blakley RL, Benkovic SJ, eds. Chemistry and Biochemistry of Folates. New York: John Wiley & Sons, 1984: 191–253.
3. Burchall JJ, Hitchings GH. Inhibitor binding analysis of dihydrofolate reductases from various species. Mol Pharmacol 1965; 1: 126–36.
4. Baccanari DP, Daluge S, King RW. Inhibition of dihydrofolate reductase: effect of reduced nicotinamide adenine dinucleotide phosphate on the selectivity and affinity of diaminopyrimidines. Biochemistry 1982; 21: 5068–75.
5. Freisheim JH, Matthews DA. The comparative biochemistry of dihydrofolate reductase. In: Sirotnak FM, Burchall JJ, Ensminger WB, Montgomery JA, eds. Folate antagonists as therapeutic agents (Vol 1). New York: Academic Press, 1984: 69–131.
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