Immunogenicity of branched polyethylene glycol modified interferon alpha

Author:

Zhou Weidong1,Lu Daru1,Liao Xiaojin2,Zhuang Lu2,Sun Li2

Affiliation:

1. School of Life Sciences, Fudan University, Shanghai, China;

2. Xiamen Amoytop Biotech Co., LTD., Xiamen, China

Publisher

Informa UK Limited

Subject

Pharmacology,Toxicology,General Medicine,Immunology,Immunology and Allergy

Reference20 articles.

1. Recommendations on risk-based strategies for detection and characterization of antibodies against biotechnology products

2. Tang M. Clinical pharmacology of biotherapeutics and data integration: Interpreting ATA. Beijing: CFDA ATA Workshop; June 7, 2013.

3. Zhou Q, Xiao L, Sun W, et al. Interferon alpha-2b modified by polyethylene glycol and methods of preparation thereof. Patent U.S.8,597,635; 2013-12-03.

4. Isolation, structural characterization, and antiviral activity of positional isomers of monopegylated interferon α-2a (PEGASYS)

5. Brugger S, Foser A, Schacher D, et al. Positional isomers of pegylated alpha interferon. Patent U.S.2004/0223950;2004-11-11.

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