Activated iRhom2 drives prolonged PM2.5 exposure-triggered renal injury in Nrf2-defective mice

Author:

Xu Min-Xuan12,Qin Yu-Ting3,Ge Chen-Xu12,Gu Ting-Ting4,Lou De-Shuai12,Li Qiang12,Hu Lin-Feng12,Li Yuan-Yuan5,Yang Wei-Wei6,Tan Jun12

Affiliation:

1. Chongqing Key Laboratory of Medicinal Resources in the Three Gorges Reservoir Region, School of Biological and Chemical Engineering, Chongqing University of Education, Chongqing, 400067, PR China;

2. Research Center of Brain Intellectual Promotion and Development for Children Aged 0-6 Years, Chongqing University of Education, Chongqing, PR China

3. School of Medicine and Pharmacy, Ocean University of China, Qingdao, PR China;

4. College of Engineering and Applied Sciences, Nanjing University, Nanjing, PR China;

5. School of Biological and Chemical Engineering, Chongqing University of Education, Chongqing, PR China;

6. Department of Nephrology, Huai’an First People’s Hospital, Nanjing Medical University, Nanjing, China;

Funder

National Natural Science Foundation of China

Chongqing Research Program of Basic Research and Frontier Technology

School-level Research Program of Chongqing University of Education

Advanced Programs of Post-doctor of Chongqing

Fundamental Research Funds for the Central Universities

Publisher

Informa UK Limited

Subject

Toxicology,Biomedical Engineering

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