Salidroside inhibits insulin resistance and hepatic steatosis by downregulating miR-21 and subsequent activation of AMPK and upregulation of PPARα in the liver and muscles of high fat diet-fed rats

Author:

Almohawes Zakiah N.1,El-Kott Attalla23,Morsy Kareem24,Shati Ali A.2,El-Kenawy Ayman E.5,Khalifa Heba S.3,Elsaid Fahmy G.26,Abd-Lateif Abd-El-Karim M.7,Abu-Zaiton Ahmed8,Ebealy Eman R.2,Abdel-Daim Mohamed M.910ORCID,Ghanem Reham A.11,Abd-Ella Eman M.712

Affiliation:

1. Biology Department, College of Science, Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia

2. Biology Department, College of Science, King Khalid University, Abha, Saudi Arabia

3. Zoology Department, College of Science, Damanhour University, Damanhour, Egypt

4. Zoology Department, College of Science, Cairo University, Cairo, Egypt

5. Pathology Department, College of Medicine, Taif University, Taif, Saudi Arabia

6. Zoology Department, Faculty of Science, Mansoura University, Mansoura, Egypt

7. Zoology Department, College of Science, Fayoum University, Fayoum, Egypt

8. Biology Department, Al-al-Bayt University, Almafraq, Jordon

9. Pharmaceutical Sciences Department, Pharmacy Program, Batterjee Medical College, Jeddah, Saudi Arabia

10. Pharmacology Department, Faculty of Veterinary Medicine, Suez Canal University, Ismailia, Egypt

11. Oral Biology Department, Faculty of Oral and Dental Medicine, Delta University for Science and Technology, Gamasa, Egypt

12. Biology Department, College of Science and Art, Al-Baha University, Al-Mandaq, Saudi Arabia

Funder

King Khalid University

Publisher

Informa UK Limited

Subject

Physiology (medical),Physiology,General Medicine

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