Lower serum alpha 1 antitrypsin levels in patients with severe COVID-19 compared with patients hospitalized due to non-COVID-19 pneumonia-Reference-Cited by-同舟云学术

Lower serum alpha 1 antitrypsin levels in patients with severe COVID-19 compared with patients hospitalized due to non-COVID-19 pneumonia

Published:2022-08-17 Issue:12 Volume:54 Page:846-851
ISSN:2374-4235
Container-title:Infectious Diseases
language:en
Short-container-title:Infectious Diseases

Author:

Pertzov Barak¹²^ORCID,Shapira Guy²³^ORCID,Abushkara Simon¹,Cohen Sharon²⁴,Turjeman Adi²⁵^ORCID,Kramer Mordechai R.¹²,Gurwitz David²^ORCID,Shomron Noam²³^ORCID

Affiliation:

1. Pulmonary institute, Rabin Medical Center, Petach Tikva, Israel

2. Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

3. Edmond J Safra Center for Bioinformatics, Tel Aviv University, Tel Aviv, Israel

4. Biochemistry and Pharmacology Laboratory, Rabin Medical Center, Petach Tikva, Israel

5. Department of Medicine E, Rabin Medical Center, Petach Tikva, Israel

Publisher

Informa UK Limited

Subject

Infectious Diseases,Microbiology (medical),General Immunology and Microbiology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/23744235.2022.2111464

Reference24 articles.

1. Mechanisms of SARS-CoV-2 entry into cells

2. SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

3. Alpha 1 Antitrypsin is an Inhibitor of the SARS-CoV-2–Priming Protease TMPRSS2

4. Alpha-1 antitrypsin inhibits TMPRSS2 protease activity and SARS-CoV-2 infection

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