Simultaneous detection of the tetrachloroethylene metabolites S-(1,2,2-trichlorovinyl) glutathione, S-(1,2,2-trichlorovinyl)-L-cysteine, and N-acetyl-S-(1,2,2-trichlorovinyl)-L-cysteine in multiple mouse tissues via ultra-high performance liquid chromatography electrospray ionization tandem mass spectrometry
Author:
Affiliation:
1. Department of Veterinary Integrative Biosciences, Texas A&M University, College Station, TX, USA
2. Department of Environmental and Occupational Health, Texas A&M University, College Station, TX, USA
Funder
National Institutes of Health
US EPA
Publisher
Informa UK Limited
Subject
Health, Toxicology and Mutagenesis,Toxicology
Link
https://www.tandfonline.com/doi/pdf/10.1080/15287394.2017.1330585
Reference36 articles.
1. Quantitation of the tetrachloroethylene metaboliteN-acetyl-S-(trichlorovinyl)cysteine in rat urinevia negative ion chemical ionization gas chromatography/tandem mass spectrometry
2. Biotransformation, excretion and nephrotoxicity of haloalkene-derived cysteine S-conjugates
3. Interstrain Differences in the Liver Effects of Trichloroethylene in a Multistrain Panel of Inbred Mice
4. Delineation of the role of metabolism in the hepatotoxicity of trichloroethylene and perchloroethylene: A dose-effect study
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