Trimethadione metabolism by human liver cytochrome P450: evidence for the involvement of CYP2E1
Author:
Publisher
Informa UK Limited
Subject
Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine
Link
http://www.tandfonline.com/doi/pdf/10.1080/004982598238930
Reference15 articles.
1. Demethylation of trimethadione and metharbital by rat liver microsomal enzymes: Substrate concentration-yield relationships and competition between substrates
2. Single-dose disulfiram inhibition of chlorzoxazone metabolism: A clinical probe for P450 2E1
3. A method for estimation of hepatic drug-metabolizing capacity: Determination of concentration of trimethadione and its metabolite in human serum.
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