Identification of cytochromes P450 involved in human liver microsomal metabolism of ecabapide, a prokinetic agent
Author:
Publisher
Informa UK Limited
Subject
Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine
Link
http://www.tandfonline.com/doi/pdf/10.1080/004982599237930
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1. Ketoconazole and sulphaphenazole as the respective selective inhibitors of P4503A and 2C9
2. Purification and characterization of the human liver cytochromes P-450 involved in debrisoquine 4-hydroxylation and phenacetin O-deethylation, two prototypes for genetic polymorphism in oxidative drug metabolism.
3. Identification of urinary metabolites of ecabapide in rat
4. Characterization of rat and human liver microsomal cytochrome P-450 forms involved in nifedipine oxidation, a prototype for genetic polymorphism in oxidative drug metabolism.
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