Characterization and management of adverse events observed with mobocertinib (TAK-788) treatment for EGFR exon 20 insertion–positive non–small cell lung cancer

Author:

Yang James Chih-Hsin1,Zhou Caicun2,Jänne Pasi A.3,Ramalingam Suresh S.4,Kim Tae Min5ORCID,Riely Gregory J6,Spira Alexander I7,Piotrowska Zofia8,Mekhail Tarek9,Garcia Campelo Maria Rosario10,Felip Enriqueta11,Bazhenova Lyudmila12ORCID,Jin Shu13,Kaur Manmit14,Diderichsen Paul M.15,Gupta Neeraj1617,Bunn Veronica18,Lin Jianchang1918ORCID,N. Churchill Eric20,Mehta Minal13,Nguyen Danny151718

Affiliation:

1. Graduate Institute of Oncology, National Taiwan University Hospital and National Taiwan University Cancer Center, Taipei, Taiwan

2. Shanghai Pulmonary Hospital, Shanghai, China

3. Dana-Farber Cancer Institute, Boston, MA, USA

4. School of Medicine, Emory University, Atlanta, GA, USA

5. Seoul National University Hospital, Seoul, South Korea

6. Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA

7. Medical Oncology, Virginia Cancer Specialists and US Oncology Research, Fairfax, VA, USA

8. Massachusetts General Hospital Cancer Center, Boston, MA, USA

9. Thoracic Cancer Program, AdventHealth Orlando, Orlando, FL, USA

10. Medical Oncology Department, Thoracic Tumors Unit, University Hospital A Coruña, CHUAC, A Coruña, Spain

11. Vall d’Hebron University Hospital, Barcelona, Spain

12. University of California San Diego Moores Cancer Center, La Jolla, CA, USA

13. Clinical Science, Oncology, Takeda Development Center Americas, Inc., Lexington, MA, USA

14. Takeda Pharmaceuticals U.S.A., Inc, Lexington, MA, USA

15. Integrated Drug Development, Certara, Princeton, NJ, USA

16. Quantitative Clinical Pharmacology, Takeda Development Center Americas, Inc., Lexington, MA, USA

17. Medical Safety Oncology, Takeda Development Center Americas, Inc., Lexington, MA, USA

18. City of Hope National Medical Center, USA

19. Oncology Statistics, Takeda Development Center Americas, Inc., Lexington, MA, USA

20. Global Medical Affairs Oncology, Takeda Pharmaceuticals U.S.A., Inc., Lexington, MA, USA

Funder

Development Center Americas Inc., Lexington

Publisher

Informa UK Limited

Subject

Pharmacology (medical),Oncology

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