Maintaining cytosolic aspartate levels is a major function of the TCA cycle in proliferating cells
Author:
Affiliation:
1. Institute of Biochemistry, Graz University of Technology, Graz, Austria
Funder
Austrian Science Fund
Austrian Science Fund (AT)
Publisher
Informa UK Limited
Subject
Cancer Research,Molecular Medicine
Link
https://tandfonline.com/doi/pdf/10.1080/23723556.2018.1536843
Reference10 articles.
1. Cancer Cell Metabolism: One Hallmark, Many Faces
2. Understanding the Intersections between Metabolism and Cancer Biology
3. Supporting Aspartate Biosynthesis Is an Essential Function of Respiration in Proliferating Cells
4. An Essential Role of the Mitochondrial Electron Transport Chain in Cell Proliferation Is to Enable Aspartate Synthesis
5. Antitumor Activity of the Glutaminase Inhibitor CB-839 in Triple-Negative Breast Cancer
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