The Deubiquitylase Otub1 Regulates the Chemotactic Response of Splenic B Cells by Modulating the Stability of the γ-Subunit Gng2

Author:

Luo Vincent M.12,Shen Connie13,Worme Samantha24,Bhagrath Aanya35,Simo-Cheyou Estelle1,Findlay Steven24,Hébert Steven26,Wai Lam Poon William24,Aryanpour Zahra2,Zhang Thomas2,Zahedi René P.78910,Boulais Jonathan11,Buchwald Zachary S.12,Borchers Christoph H.131415,Côté Jean-Francois11161718,Kleinman Claudia L.26,Mandl Judith N.135,Orthwein Alexandre1241214

Affiliation:

1. Department of Microbiology and Immunology, McGill University, Montréal, Québec, Canada

2. Lady Davis Institute for Medical Research, Jewish General Hospital, Montréal, Québec, Canada

3. McGill Research Centre for Complex Traits, McGill University, Montréal, Québec, Canada

4. Division of Experimental Medicine, McGill University, Montréal, Québec, Canada

5. Department of Physiology, McGill University, Montréal, Québec, Canada

6. Department of Human Genetics, McGill University, Montréal, Québec, Canada

7. Manitoba Centre for Proteomics & Systems Biology, University of Manitoba, Winnipeg, Manitoba, Canada

8. Department of Internal Medicine, University of Manitoba, Winnipeg, Manitoba, Canada

9. Department of Biochemistry and Medical Genetics, University of Manitoba, Winnipeg, Manitoba, Canada

10. CancerCare Manitoba Research Institute, Winnipeg, Manitoba, Canada

11. Institut de Recherches Cliniques de Montréal (IRCM), Montreal, Québec, Canada

12. Department of Radiation Oncology, Winship Cancer Institute, Emory University, Atlanta, Georgia, USA

13. Segal Cancer Proteomics Centre, Lady Davis Institute for Medical Research, McGill University, Montréal, Québec, Canada

14. Gerald Bronfman Department of Oncology, Lady Davis Institute for Medical Research, Jewish General Hospital, Montréal, Québec, Canada

15. Department of Pathology, McGill University, Montreal, Québec, Canada

16. Department of Anatomy and Cell Biology, McGill University, Montreal, Québec, Canada

17. Département de Biochimie et Médecine Moléculaire, Université de Montréal, Montreal, Québec, Canada

18. Département de Médecine (Programmes de Biologie Moléculaire), Université de Montréal, Montreal, Québec, Canada

Publisher

Informa UK Limited

Subject

Cell Biology,Molecular Biology

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