Balancing renal Ang-II/Ang-(1–7) by xanthenone; an ACE2 activator; contributes to the attenuation of Ang-II/p38 MAPK/NF-κB p65 and Bax/caspase-3 pathways in amphotericin B-induced nephrotoxicity in rats-Reference-Cited by-同舟云学术

Balancing renal Ang-II/Ang-(1–7) by xanthenone; an ACE2 activator; contributes to the attenuation of Ang-II/p38 MAPK/NF-κB p65 and Bax/caspase-3 pathways in amphotericin B-induced nephrotoxicity in rats

Published:2023-02-22 Issue:6 Volume:33 Page:452-462
ISSN:1537-6516
Container-title:Toxicology Mechanisms and Methods
language:en
Short-container-title:Toxicology Mechanisms and Methods

Author:

Azouz Amany A.¹,Abdel-Rahman Doaa M.¹,Messiha Basim Anwar Shehata¹

Affiliation:

1. Department of Pharmacology & Toxicology, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt

Publisher

Informa UK Limited

Subject

Health, Toxicology and Mutagenesis,Toxicology

Link

https://www.tandfonline.com/doi/pdf/10.1080/15376516.2023.2177218

Reference56 articles.

1. Xanthenone, ACE2 activator, counteracted gentamicin-induced nephrotoxicity in rats: Impact on oxidative stress and ACE2/Ang-(1–7) signaling

2. Modulation of brain ACE and ACE2 may be a promising protective strategy against cerebral ischemia/reperfusion injury: an experimental trial in rats

3. Benzbromarone mitigates cisplatin nephrotoxicity involving enhanced peroxisome proliferator-activated receptor-alpha (PPAR-α) expression

4. Drug and herbal medicine-induced nephrotoxicity in children; review of the mechanisms

5. Encochleated Amphotericin B: Is the Oral Availability of Amphotericin B Finally Reached?

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