Mitochondria-dependent apoptosis in triptolide-induced hepatotoxicity is associated with the Drp1 activation

Author:

Hasnat Muhammad12,Yuan Ziqiao1,Ullah Aftab3,Naveed Muhammad4ORCID,Raza Faisal3,Baig Mirza Muhammad Faran Ashraf5,Khan Asifullah3,Xu Dengqiu1,Su Yuwen67,Sun Linxin18,Zhang Luyong19,Jiang Zhenzhou110ORCID

Affiliation:

1. Jiangsu Key Laboratory of Drug Screening, China Pharmaceutical University, Nanjing, China;

2. Institute of Pharmaceutical Sciences, University of Veterinary and Animal Sciences, Lahore, Pakistan;

3. State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China;

4. Department of Clinical Pharmacology, School of Pharmacy, Nanjing Medical University, Nanjing, China;

5. State Key Lab of Analytical Chemistry for Life Sciences, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, China;

6. School of Pharmacy, Nanjing Medical University, Nanjing, China;

7. Department of Clinical Pharmacology, Sir Run Run Hospital, Nanjing Medical University, Nanjing, China;

8. Jiangsu Center for Pharmacodynamics Research and Evaluation, China Pharmaceutical University, Nanjing, China;

9. Center for Drug Screening and Pharmacodynamics Evaluation, School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, China;

10. Key Laboratory of Drug Quality Control and Pharmacovigilance, China Pharmaceutical University, Nanjing, China

Publisher

Informa UK Limited

Subject

Health, Toxicology and Mutagenesis,Toxicology

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