Urinary crystal formation and urothelial effects of pyroxasulfone administered to male rats

Author:

Kyoya Takahiro1,Arnold Lora L.2,Pennington Karen L.2,Kakiuchi-Kiyota Satoko23,Terada Megumi1,Abe Koichi1,Cohen Samuel M.24ORCID

Affiliation:

1. Kumiai Chemical Industry Co., Ltd, Shizuoka, Japan and Tokyo

2. Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, USA

3. Safety Assessment, Genentech Inc, South San Francisco, CA, USA

4. Havlik-Wall Professor of Oncology and Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, USA

Funder

Kumiai Chemical Industry Co., Ltd

Publisher

Informa UK Limited

Subject

Health, Toxicology and Mutagenesis,Toxicology

Reference32 articles.

1. Aoshima T. 2010. Pyroxasulfone (KIH-485) investigative study: investigation for cell proliferation and oxidative stress in rat urinary bladder after dietary exposure for 14 days. Biosafety Research Center, Foods, Drugs, and Pesticides.

2. Australian Pesticides and Veterinary Medicines Authority (APVMA). 2011. Public Release Summary on the evaluation of the new active pyroxasulfone in the product Sakura®850 WG Herbicide. APVMA Product Number 63998, October.

3. Tributyl Phosphate Effects on Urine and Bladder Epithelium in Male Sprague–Dawley Rats

4. Carpenter C. 2007a. KIH-485TGAI (Pyroxasulfone as provisionally approved): acute dermal irritation study in rabbits. DuPont Haskell Global Centers for Health and Environmental Sciences, E.I. DuPont de Nemours & Company. Report No. 22322.

5. Carpenter C. 2007b. KIH-485TGAI (Pyroxasulfone as provisionally approved): acute eye irritation study in rabbits. DuPont Haskell Global Centers for Health and Environmental Sciences, E.I. DuPont de Nemours & Company. Report No. 22448.

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